| No. | API | Intermediates | Cas No. |
| 1 | Axitinib | 3-Iodo-6-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole | 886230-74-6 |
| 3-Iodo-6-nitroindazole | 70315-70-7 | ||
| N-methyl-2-sulfanylbenzamide | 20054-45-9 | ||
| 2 | Carfilzomib | BOC-L-Leucine | 13139-15-6 |
| Methyl L-phenylalaninate hydrochloride | 7524-50-7 | ||
| Boc-L-homophenylalanine | 100564-78-1 | ||
| CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester | 247068-82-2 | ||
| (alphaS)-alpha-[(4-Morpholinylacetyl)aMino]benzenebutanoyl-L-leucyl-L-phenylalanine | 868540-16-3 | ||
| (alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) | 868539-99-5 | ||
| (alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester | 868539-98-4 | ||
| 3 | Ceritinib | 2,5-Dichloro-N-[2-[(1-methylethyl)thio]phenyl]-4-pyrimidinamine | 1632485-14-3 |
| 5-Methyl-2-(1-methylethoxy)-4-(4-piperidinyl)benzenamine hydrochloride | 1380575-45-0 | ||
| 4 | Dasatinib | 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | 302964-24-5 |
| 5 | Erlotinib | 2-Amino-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester hydrochloride | 183322-17-0 |
| 3-Aminophenylacetylene | 54060-30-9 | ||
| 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone | 179688-29-0 | ||
| 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline | 183322-18-1 | ||
| Ethyl 4,5-bis(2-methoxyethoxy)-2-aminobenzoate | 179688-27-8 | ||
| 6 | Gefitinib | 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one | 199327-61-2 |
| 7 | Gemcitabine | 2-Deoxy-2,2-difluoro pentofuranos-1-ulose-3,5-dibenzoate （T6） | 122111-01-7 |
| 2-Deoxy-2,2-difluoro-D-ribofuranose- 3,5-dibenzoate-1-methanesulphonate(T8) | 122111-11-9 | ||
| 2’2’-Difluoro-2’-Deoxycytidine-3’,5’-Dibenzoate (T9) | 134790-39-9 | ||
| Gemcitabine base(T11) | 95058-81-4 | ||
| 8 | Lapatinib | 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde | 231278-84-5 |
| 2-Formylfuran-5-boronic acid | 27329-70-0 | ||
| 9 | Lenalidomide | Lenalidomide | 191732-72-6 |
| Methyl 2-bromomethyl-3-nitrobenzoate | 98475-07-1 | ||
| 2,6-Dioxopiperidine-3-ammonium chloride | 24666-56-6 | ||
| 3-aminopiperidine-2,6-dione hydrochloride | 24666-56-6 | ||
| 10 | Sunitinib | N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide | 356068-86-5 |
| 11 | Tedizolid | 5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine | 380380-64-3 |
| (5R)-3-(4-Bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one | 444335-16-4 | ||
| (5R)-3-(3-fluoro-4-iodophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one | 487041-08-7 | ||
| 12 | Tofacitinib | 4-Chloropyrrolo[2,3-d]pyrimidine | 3680-69-1 |
| 13 | Darunavir | (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane | 98737-29-2 |
| 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide | 169280-56-2 | ||
| Tert-Butyl [(1S,2R)-1-Benzyl-2-hydroxy-3-(isobutylamino)propyl]carbamate | 160232-08-6 | ||
| 14 | Dolutegravir | (R)-3-Aminobutan-1ol | 61477-40-5 |
| 15 | Efavirenz | E2: 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride | 173676-59-0 |
| E6: (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol | 209414-27-7 | ||
| 16 | Enzalutamide | 3-Fluoro-4-methylphenylisothiocyanate | 143782-23-4 |
| 4-Bromo-2-fluoro-N-methylbenzamide | 749927-69-3 | ||
| N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester | 1332524-01-2 | ||
| 4-amino-2-fluoro-n-methylbenzamide | 915087-25-1 | ||
| 4-[(1-Cyano-1-methylethyl)amino]-2-fluoro-N-methylbenzamide | 915087-32-0 | ||
| 17 | Finasteride | 3-oxo -4-aza-5-alpha androstone -17-beta-carboxylic acid (F9 acid) | 103335-55-3 |
| 18 | Ledipasvir | (1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane -2-carboxylic acid 1,1-dimethyl |
1256387-74-2 |
| (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid | 1129634-44-1 | ||
| 19 | LCZ696 | (3R,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | 1038924-70-7 |
| (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid | 1012341-50-2 | ||
| 20 | Palbociclib | 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one | 1016636-76-2 |
| Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate | 571189-16-7 | ||
| 21 | PCI-32765 | (S)-1-Boc-3-hydroxypiperidine | 143900-44-1 |
| 4-Aminopyrazolo[3,4-d]pyrimidine | 2380-63-4 | ||
| 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine | 330786-24-8 | ||
| 22 | Posaconazole | (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofur | 149809-43-8 |
| 2-{(1S,2S)-1-Ethyl2-bezyloxy propyt}-2,4_dihydro_4_{4_{4-(4-hydroxyphenyl)-1- | 184177-83-1 | ||
| 23 | Sitagliptin | Meldrum's acid | 2033-24-1 |
| 2,4,5-Trifluorophenylacetic acid | 209995-38-0 | ||
| 3-(trifluoromethyl)-5,6,7,8-tetrahydro-(1,2,4)triazolo(4,3-a)pyrazine hydrochloride | 762240-92-6 | ||
| 24 | Sofosbuvir | (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate | 874638-80-9 |
| 2’-deoxy-2’-fluoro-2’-C-methyluridine | 863329-66-2 | ||
| N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)- phenoxyphosphinyl]-L-alanine-1-methylethyl ester | 1334513-02-8 | ||
| 25 | Aripiprazole | 1-(2,3-Dichlorophenyl)piperazine monohydrochloride | 119532-26-2 |
| 7-Hydroxyquinolinone | 22246-18-0 | ||
| 26 | Duloxetine | 3-(Dimethylamino)-1-(2-thienyl)-1-propanol | 13636-02-7 |
| (S)-3-(dimethylamino)-1-(2-thienyl)-1-propanol | 132335-44-5 | ||
| 1-fluoronaphthalene | 321-38-0 | ||
| 27 | Lubiprostone | L6:16,16-difluoro-9,15-dihydroxy-11-[(tetrahydro-2H-pyran-2-yl)oxy](5Z,9a,11a)-(9Cl)-prost-5-en-1-oic acid, benzyl ester | 136790-77-7 |
| 28 | Paliperidone | 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one | 130049-82-0 |
| 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride | 84163-13-3 | ||
| 29 | Pemetrexed disodium | 4-[2-(2-Amino-4,7-Dihydro-4-Oxo-1H-Pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid | 137281-39-1 |
| 30 | Netupitant | 2-(3,5-bis(trifluoroMethyl)phenyl)-2-Methyl propanoic acid | 289686-70-0 |
| N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine | 290297-25-5 | ||
| 4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide | 342417-01-0 | ||
| 31 | Rosuvastatin Calcium | Z-8:4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino] pyriminl-5-yl- phosphine oxide | 147118-37-4 |
| J-6:Methyl(3r)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanoate | 147118-35-2 | ||
| Z-7: 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol | 147118-36-3 | ||
| D-5:(4r-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-aceticacid,1,1-dimethyethyl ester | 124665-09-0 | ||
| 32 | Valsartan | L-Valine methyl ester hydrochloride(LVME) | 6306-52-1 |
| L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl]methyl]-, methyl ester, monohydrochloride (CMVEH) | 482577-59-3 | ||
| Valsartan Methyl Ester (VME) | 137863-17-3 | ||
| Trityl Valsartan Methyl Ester (TVME) | 781664-81-1 | ||
| 33 | Vidagliptin | L-PROLINE AMIDE | 7531-52-4 |
| 3-AMINO-1-ADAMANTANOL | 702-82-9 | ||
| 34 | Vilazodone | 5-Cyanoindole | 15861-24-2 |
| 3-(4-Chlorbutyl)-1H-indol-5-carbonitril | 143612-79-7 | ||
| Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate | 163521-20-8 | ||
| 35 | Terbinafine | 1-Chloro-6,6-dimethyl-2-heptene-4-yne | 83554-69-2 |
| 36 | TicargreIor | 2-(((3ar,4s,6r,6as)-6-aminotetrahydro-2,2-dimethyl-4h-cyclopenta-1,3-dioxol-4-yl)oxy)-ethanol (2r,3r)-2,3-dihydroxybutanedioate | 376608-65-0 |
| 4,6-dichloro-2-(propylthio)pyrimidin-5-amine | 145783-15-9 | ||
| 2-(((3ar,4s,6r,6as)-6-((5-amino-6-chloro-2-(propylthio)-4-pyrimidinyl)amino)tetrahydro-2,2-dimethyl-4h-cyclopenta-1,3-dioxol-4-yl)oxy)-ethanol | 376608-74-1 | ||
| (1r,2s)-2-(3,4-difluorophenyl)cyclopropanaminium(2r)-hydroxy(phenyl)ethanoate | 376608-71-8 |
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